
If you’ve been browsing social media lately, you’ve probably seen the Anua Niacinamide 10% + TXA 4% Serum everywhere, especially in the Korean skincare circles.
And if you’re dealing with hyperpigmentation, acne scars, or redness, you’re probably pondering whether to try it or not.
But does it actually deliver results?
And how does it compare to the equally popular serums: The Ordinary Niacinamide 10% + Zinc 1% or Axis-Y Dark Spot Correcting Glow Serum?
These are some of the questions we will be answering here.
We’re going to break down exactly what makes this formula a standout and the key things you’ll need to know before adding it to your routine.
What Is Anua Niacinamide Serum?
The Anua Niacinamide 10% + TXA 4% is a brightening, barrier-repairing treatment serum. It tackles pigmentation with a “multi-modal approach,” meaning it uses several active ingredients that work in different ways for more thorough results. It blocks pigment transfer with tranexamic acid and niacinamide, reduces melanin production thanks to alpha arbutin, and strengthens your skin barrier with niacinamide and polyglutamic acid.
The consistency is lightweight and watery, and it absorbs quickly into the skin (within 30-60 seconds) without any greasy feel. Its natural peachy-pink tint comes from Vitamin B12, giving your skin a subtle, radiant finish immediately after application. Plus, many find it layers beautifully under makeup and plays well with other products, so you won’t have to worry about pilling.
Key Ingredients:
- 10% Niacinamide for barrier repair and oil control
- 4% Tranexamic Acid for pigmentation reduction
- 2% Alpha Arbutin for melanin inhibition
- Polyglutamic Acid and Hyaluronic Acid for hydration
- Let’s take a closer look at what each ingredient does.
Ingredient Breakdown: What Makes It Work?
This serum packs a punch with a blend of active ingredients like tranexamic acid, niacinamide, polyglutamic acid, and alpha arbutin, all specifically chosen to tackle hyperpigmentation, irritation, and moisture loss.
It doesn’t just rely on one approach; it simultaneously blocks pigment transfer, reduces melanin production, and strengthens your skin barrier. This multi-pronged action delivers more comprehensive results than other single-ingredient treatments you’ll find.
Niacinamide (10%)
At a 10% concentration, Niacinamide (Vitamin B3) truly shines as both an antioxidant and an anti-inflammatory. Its role is to effectively strengthen your skin’s barrier, which is a major factor in reducing redness and irritation.
- Function: Regulates oil production, strengthens skin barrier, fades dark spots and acne scarring, reduces redness and inflammation
- In This Formulation: 10% is higher than the typical 2-5% concentration found in most products. Higher percentages don’t necessarily mean better results and may cause irritation if your skin is sensitive.
Tranexamic Acid (TXA) (4%)
Tranexamic acid is an often-overlooked yet powerful ingredient that tackles dark spots. You’ll find it here at a potent 4% concentration (higher than the typical 2-3% in most brands). This makes the serum an excellent choice if your main concern is hyperpigmentation.
This synthetic derivative of the amino acid lysine doesn’t just target dark spots; it also helps with persistent facial redness often linked to rosacea and post-acne marks. It achieves this by disrupting the transfer of pigment between skin cells and limiting the growth of excess blood vessels. The result? Reduced visible redness and a more even skin tone.
- Function: Blocks melanin transfer between cells, reduces inflammation
- In This Formulation: 4% concentration is higher than other competitors (typically 2-3%)
- Benefits: Very effective in dealing with stubborn dark spots and post-inflammatory hyperpigmentation
Alpha Arbutin (2%)
Derived from bearberry extract, Alpha Arbutin is a gentler alternative to tackle dark spots compared to harsher hydroquinone (a skin depigmentation agent). It actively blocks tyrosinase, the enzyme responsible for melanin production in your skin. By interrupting this process, alpha arbutin effectively reduces the appearance of dark spots and promotes a more even skin tone.
- Function: Inhibits the tyrosinase enzyme to prevent new melanin formation
- Why it’s included: Enhances the brightening effects of niacinamide and TXA
Vitamin B12 (Cyanocobalamin)
The serum’s unique pink hue comes from Vitamin B12 (Cyanocobalamin). Beyond its colour, Vitamin B12 has shown promise in addressing atopic dermatitis, actively helping to reduce redness, itching, and scaling.
- Benefits: Shows promise for improving symptoms of sensitive skin conditions
- Added value: May help reduce itching and irritation in reactive skin types
Hydrating Agents
- Polyglutamic Acid (PGA): This ingredient boasts powerful hydrating properties, locking in moisture and holding up to four times more hydration than hyaluronic acid. It has a larger molecule size which enables it to form a protective barrier on your skin’s surface and even help slow the breakdown of your skin’s natural hyaluronic acid, supporting firmness and elasticity. As a result, your skin feels softer, looks more plump, and stays better hydrated throughout the day.
- Hyaluronic Acid: Provides additional hydration and plumping effects.
Who is Anua Niacinamide 10% + TXA 4% Serum For?
With its high percentage of niacinamide and the powerful brightening agents Tranexamic Acid (TXA) and Alpha Arbutin, this serum is designed to help you tackle:
- Post-acne marks and scarring
- Melasma or age spots
- Redness from rosacea or sensitivity
- Uneven skin tone
- Oily or combination skin
Keep in Mind: Although niacinamide supports skin barrier, the 10% concentration found here might cause initial irritation or drying for severely compromised dry skin. You might need to buffer it with a moisturiser or a hydrating toner.
If you’re unsure what ingredients you need for your skin type, we’ve got you covered.
How to Use Anua Niacinamide 10% + TXA 4% Serum in Your Routine?

You can use it as part of either a morning or evening routine:
- Cleanse your face thoroughly
- Apply toner (optional)
- Use 2-3 drops on slightly damp skin
- Follow with moisturiser
- Always use SPF 30+ during the day
How Does It Compare to Competitors?
vs. The Ordinary Niacinamide 10% + Zinc 1%

Formulation: Both products are designed to enhance skin brightness however, the more complex formula of Anua gives it an edge over The Ordinary’s minimal approach.
- Anua (key ingredients): 10% Niacinamide, 4% Tranexamic Acid, 2% Alpha Arbutin, Polyglutamic Acid
- The Ordinary (key ingredients): 10% Niacinamide, 1% Zinc PCA
Texture: The Ordinary has a thicker, more viscous texture, which can feel tacky when it dries down to a matte finish. The Anua on the other hand, is more lightweight. allowing it to absorb quicker without stickiness.
Winner: Anua’s formulation is more effective in fighting hyperpigmentation.
vs. Axis-Y Dark Spot Correcting Glow Serum
Formulation: Both products target dark spots and hyperpigmentation, with Anua’s higher concentration giving it a more potent advantage over Axis-Y’s gentler philosophy.
- Anua (key ingredients): 10% Niacinamide, 4% Tranexamic Acid, 2% Alpha Arbutin, Polyglutamic Acid
- Axis-Y (key ingredients): 5% Niacinamide, Plant-derived Squalane, Papaya Enzyme, Rice Bran Extract, Glycyrrhiza Glabra Root Extract
Texture: Axis-Y has a lightweight, watery consistency that absorbs quickly and provides a natural glow finish. Anua is also lightweight but slightly more viscous however it absorbs without stickiness while delivering intense hydration.
Winner: Anua’s formulation is more potent for serious hyperpigmentation concerns.

FAQ
“It’s Too Strong for My Skin”
If your skin is feeling a bit overwhelmed, try adjusting how often you apply the serum. Reducing frequency to 2-3 times per week can make a big difference. You can also layer a hydrating toner underneath to provide a buffer. And if irritation persists, consider switching to a lower niacinamide concentration.
“I’m Not Seeing Results”
If you’re not seeing results as quickly as you’d like, remember that consistency is key as pigmentation takes 8-12 weeks to show significant improvement. Additionally, missing applications can slow progress, and some spots, like melasma, fade slower than post-acne marks.
And always apply SPF, as continued sun exposure will counteract any progress.
“It Pills Under My Moisturiser and/or It Takes Forever to Absorb”
Try waiting 5-10 minutes between applying your serum and moisturiser, allowing each product ample time to absorb. You might also be using too much; aim for just 2-3 drops of serum. Additionally, opting for a lighter-weight moisturiser can prevent pilling, and applying your serum to slightly damp skin often improves absorption.
Bottom Line
The Anua Niacinamide 10% + TXA 4% Serum delivers on its promise.
This serum is designed with a strategic blend, where each ingredient tackles discolouration, moisture, and irritation in different ways. The combination of multiple active ingredients creates what’s called a “multi-modal approach” to treating pigmentation. Rather than relying on a single mechanism, this serum simultaneously blocks pigment transfer (tranexamic acid + niacinamide), reduces melanin production (alpha arbutin), and strengthens the skin barrier (niacinamide + polyglutamic acid) for complete results.
Reported side effects are minimal, usually just mild redness or peeling that often settles down with a good moisturiser. Given the choice and strength of its active ingredients, the Anua Niacinamide 10% + TXA 4% Serum does particularly well in dealing with stubborn pigment or persistent redness. However, if you have very sensitive skin, you should always patch test first.